Funding for this research was provided by:
RCUK | Biotechnology and Biological Sciences Research Council (BB/M000176/2)
RCUK | Medical Research Council (MC_PC_17156)
Received: 11 March 2021
Accepted: 3 June 2021
First Online: 23 June 2021
: The authors M.W., N.M. and D.G. declare the following competing interest: they are employees of, and shareholders in, AstraZeneca. The remaining authors declare no competing interests.