Toffoli, Marco http://orcid.org/0000-0002-3255-9648
Chen, Xiao
Sedlazeck, Fritz J. http://orcid.org/0000-0001-6040-2691
Lee, Chiao-Yin http://orcid.org/0000-0003-1117-3006
Mullin, Stephen
Higgins, Abigail http://orcid.org/0000-0003-1908-5721
Koletsi, Sofia
Garcia-Segura, Monica Emili
Sammler, Esther
Scholz, Sonja W.
Schapira, Anthony H. V.
Eberle, Michael A. http://orcid.org/0000-0001-8965-1253
Proukakis, Christos http://orcid.org/0000-0001-6423-6539
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (1ZIANS003154)
RCUK | MRC | Medical Research Foundation (MR/T046007/1)
Article History
Received: 28 December 2021
Accepted: 21 June 2022
First Online: 6 July 2022
Competing interests
: XC and MAE were employees of Illumina Inc. during the research and writing of this manuscript and are now employees of Pacific Biosciences Inc. SWS serve on the Scientific Advisory Council of the Lewy Body Dementia Association. SWS is an editorial board member for the Journal of Parkinson’s Disease and JAMA Neurology. AHVS is supported by the UCLH NIHR BRC. MT, FJS, C-YL, SM, AH, SK, MEG-S, ES and CP declare no competing interests.
: Ethics approval was provided by the National Research Ethics Service London—Hampstead Ethics Committee for RAPSODI, NRES Committee central—London for QSBB samples and UCL Ethics Committee for PPMI samples. All participants provided informed consent.