Vasilescu, Catalina
Colpan, Mert http://orcid.org/0000-0003-0698-5018
Ojala, Tiina H. http://orcid.org/0000-0001-9092-7763
Manninen, Tuula
Mutka, Aino http://orcid.org/0000-0002-2885-3211
Ylänen, Kaisa
Rahkonen, Otto
Poutanen, Tuija http://orcid.org/0000-0002-0805-0569
Martelius, Laura
Kumari, Reena
Hinterding, Helena
Brilhante, Virginia
Ojanen, Simo
Lappalainen, Pekka http://orcid.org/0000-0001-6227-0354
Koskenvuo, Juha
Carroll, Christopher J.
Fowler, Velia M.
Gregorio, Carol C. http://orcid.org/0000-0002-0044-2074
Suomalainen, Anu http://orcid.org/0000-0003-4833-5195
Funding for this research was provided by:
Jane ja Aatos Erkon Säätiö
Sigrid Juséliuksen Säätiö
University of Helsinki | Helsingin Yliopiston Tiedesäätiö
Academy of Finland
Finnish Cultural Foundation | Etelä-Karjalan Rahasto
Alfred Kordelinin Säätiö
Maud Kuistilan Muistosäätiö
Lastentautien Tutkimussäätiö
U.S. Department of Health & Human Services | National Institutes of Health (R01HL123078, R01HL164644)
U.S. Department of Health & Human Services | National Institutes of Health
American Heart Association (19POST34450023)
Article History
Received: 20 April 2023
Accepted: 4 December 2023
First Online: 2 January 2024
Competing interests
: The authors declare the following competing interests: J.K. is co-founder and director of Blueprint Genetics, which offers genetic diagnostics for inherited disorders. The other authors declare no competing interests.
: The study plan of the Childhood Cardiomyopathy project was approved by the Child and Adolescent Psychiatry Ethical Board and Coordinating Ethical Board of Helsinki University Hospital and received the ethical permit numbers 291/13/03/03/2008 and 254/13/03/00/14. All the samples were taken for diagnostic purposes with informed consent from parents and from patients when they were older than 10 years of age. All ethical regulations relevant to human research participants were followed. The work with animals was performed under the approval by The Institutional Animal Care and Use Committee at the University of Arizona, Protocol number 08-017, which conformed to all applicable federal and institutional policies, procedures and regulations, including the Public Health Service Policy on Humane Care and Use of Laboratory Animals, United States Department of Agriculture regulations (9 CFR Parts 1, 2, 3), the Federal Animal Welfare Act (7 USC 2131 et. Seq.), the Guide for the Care and Use of Laboratory Animals, and all relevant institutional regulations and policies regarding animal care and use at the University of Arizona.