Park, Cana
Hahn, Oliver
Gupta, Shweta
Moreno, Arturo J.
Marino, Francesca
Kedir, Blen http://orcid.org/0000-0003-1654-2149
Wang, Dan
Villeda, Saul A. http://orcid.org/0000-0002-2726-9582
Wyss-Coray, Tony http://orcid.org/0000-0001-5893-0831
Dubal, Dena B. http://orcid.org/0000-0001-7504-4372
Funding for this research was provided by:
U.S. Department of Health & Human Services | National Institutes of Health (NS092918, NIH/NCATS UL1 TR001872)
American Federation for Aging Research
Simons Foundation
Coulter-Weeks, Bradley, Godsoe, and Bakar Family Foundations; Bakar Aging Research Institute.
Article History
Received: 12 June 2023
Accepted: 13 July 2023
First Online: 16 August 2023
Competing interests
: The Regents of the University of California hold an issued patent on ‘Methods and compositions for improved cognition’ involving klotho (US10864256B2, Inventor D.B.D.) and have applied for a provisional patent applications related to the content of the manuscript findings, ‘Platelet factors and cognitive improvement’ (PCT/US2021/017580, coinventors C.P., S.V. and D.B.D.) and ‘Use of downstream factors in the klotho pathway to assess klotho activity’ (PCT/US2021/020706, inventor D.B.D.). The rest of the authors (O.H., S.G., A.J.M., F.M., B.K. and T.W.-C.) have no competing interests related to the manuscript. D.B.D. consulted for Unity Biotechnology (unrelated to content of manuscript) and SV Health Investors.