Ahluwalia, Manmeet S. http://orcid.org/0000-0003-3794-9511
Rogers, Lisa R.
Chaudhary, Rekha
Newton, Herbert
Ozair, Ahmad http://orcid.org/0000-0001-6570-4541
Khosla, Atulya A. http://orcid.org/0000-0002-8373-4290
Nixon, Andrew B.
Adams, Bonne J.
Seon, Ben K.
Peereboom, David M.
Theuer, Charles P.
Funding for this research was provided by:
Case Comprehensive Cancer Center, Case Western Reserve University (N/A)
Article History
Received: 22 February 2023
Accepted: 4 August 2023
First Online: 8 September 2023
Competing interests
: M.S.A.<b>:</b> Grant Funding by AstraZeneca, BMS, Bayer, Incyte, Pharmacyclics, Novocure, Mimivax, Merck, and TRACON pharmaceuticals. Consultation: Bayer, Novocure, Kiyatec, Insightec, GSK, Xoft, Nuvation, Cellularity, SDP Oncology, Apollomics, Prelude, Janssen, Tocagen, Voyager Therapeutics, Viewray, Caris Lifesciences, Pyramid Biosciences, Varian Medical Systems, Cairn Therapeutics, Anheart Therapeutics, Theraguix. Scientific Advisory Board member for Cairn Therapeutics, Pyramid Biosciences, and Modifi Biosciences. Stock shareholder for Mimivax, Cytodyn, and MedInnovate Advisors LLC. D.M.P.: <i>Consulting or Advisory Role</i>: Orbus Therapeutics, Sumitomo Dainippon Pharma Oncology Inc, Stemline Therapeutics, Novocure. <i>Grant Funding</i>: Pfizer (Inst), Novartis (Inst), Neonc Technologies (Inst), Orbus Therapeutics (Inst), Bristol Myers Squibb (Inst), Genentech/Roche (Inst), Pharmacyclics (Inst), Bayer (Inst), Karyopharm Therapeutics (Inst), Apollomics (Inst), Vigeo Therapeutics (Inst), Global Coalition for Adaptive Research (Inst), MimiVax (Inst), Ono Pharmaceutical (Inst), Mylan (Inst). A.B.N. has received research funding from Genentech, HTG Molecular Diagnostics, MedImmune/AstraZeneca, Medpacto, Promega Corporation, Seattle Genetics and TRACON pharmaceuticals; and has received consultant/advisory compensation from AdjuVolt Therapeutics, Eli Lilly, GSK, Leap Therapeutics, Promega Corporation. M.S.A., L.R.R., R.C., and H.N. received institutional funding from TRACON for this clinical trial. B.K.S. is the inventor of TRC105. B.J.A. and C.P.T. are employees of TRACON Pharmaceuticals, Inc. TRACON pharmaceuticals helped sponsor the trial and performed the data analysis. However, the funders had no role in the interpretation of trial results or the writing of the manuscript. The rest of the authors have no competing interests to declare.