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Aquaporin-4 Knockdown in the Substantia Nigra Exacerbates α-Synuclein Pathology, Neurodegeneration, and Motor Dysfunction in a Rat Model of Parkinson’s Disease

Crossref DOI link: https://doi.org/10.1134/S0022093025050035

Published Online: 2025-11-05

Published Print: 2025-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lapshina, K. V.

Khanina, M. V.

Guzeev, M. A.

Kaismanova, M. P.

Ekimova, I. V.
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Text and Data Mining valid from 2025-10-01

Version of Record valid from 2025-10-01
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Article History

Received: 25 July 2025

Revised: 2 September 2025

Accepted: 3 September 2025

First Online: 5 November 2025

ETHICS APPROVAL

: Animal experiments were carried out in compliance with the NIH Guidelines for the care and use of laboratory animals (http://oacu.od.nih.gov/regs/index.htm), as well as the requirements of the Basel Declaration and legal acts of the Russian Federation. Experimental protocols were approved by the Bioethics Committee of Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences (Minutes no. 1–12/2023, meeting no. 1 of January 26, 2023).

: The authors of this work declare that they have no conflicts of interest.

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