Document is current

Article History

Received: 2 February 2023

Revised: 7 March 2023

Accepted: 9 March 2023

First Online: 30 August 2023

COMPLIANCE WITH ETHICAL STANDARDS

: Conflict of interest. The authors declare that they have no conflicts of interest.

: Ethical approval. Maintenance of experimental animals and all procedures were performed in accordance with the international rules for the treatment of animals in the Guide for the Care and Use of Laboratory Animals, Eighth Edition, Committee for the Update of the Guide for the Care and Use of Laboratory Animals; National Research Council © 2011 National Academy of Sciences (United States). The work with animals was regulated by the following documents: “Rules of good laboratory practice in the Russian Federation” approved by order of the Ministry of Health of the Russian Federation No. 199n of January 4, 2016; interstate standards GOST 33215-2014 “Guidelines for the maintenance and care of laboratory animals” (Rules for equipping premises and organizing procedures, date of introduction January 7, 2015). Animal conditions and the experiments carried out were approved by the Commission on Bioethics of the Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences.