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Article History

Received: 13 November 2024

Revised: 24 December 2024

Accepted: 3 March 2025

First Online: 12 November 2025

ETHICS APPROVAL AND CONSENT TO PARTICIPATE

: Ethical approval. The maintenance of experimental animals and all procedures were performed in accordance with international rules for the treatment of animals “Guide for the Care and Use of Laboratory Animals, Eight Edition, Committee for the Update of the Guide for the Care and Use of Laboratory Animals”; “National Research Council © 2011 National Academy of Sciences” (United States). Work with animals was also regulated by the following documents: “Rules of Good Laboratory Practice in the Russian Federation,” approved by order of the Ministry of Health of the Russian Federation No. 199n dated April 1, 2016; interstate standards GOST 33215-2014 “Guidelines for the maintenance and care of laboratory animals” (Rules for equipping premises and organizing procedures, dated July 1, 2015). The conditions for keeping animals and the experimental procedures performed were approved by the Bioethics Commission of the ICG SB RAS (protocol No. 88 of September 24, 2021).

: The authors declare that they have no conflict of interest.