Funding for this research was provided by:
Ministry of Science and Technology, Taiwan (MOST 105-2314-B-002 -046, MOST 105-2314-B-002 -098 -MY3)
Received: 31 July 2018
Accepted: 24 January 2019
First Online: 13 February 2019
Ethics approval and consent to participate
: The study was approved by the Institutional Animal Care and Use Committee, National Taiwan University College of Medicine. All experiments were performed according to relevant guidelines and regulations.
: There is no contains about any individual person’s data in any form and there is no need to get consent for publication.
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.