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Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death

Published Online: 2024-10-25

Authors

Martínez, Pablo https://orcid.org/0000-0003-3496-4652
Silva, Mónica

Abarzúa, Sebastián

Tevy, María Florencia

Jaimovich, Enrique

Constantine-Paton, Martha

Bustos, Fernando J. https://orcid.org/0000-0002-0487-7032
van Zundert, Brigitte https://orcid.org/0000-0002-4129-9972
Funding

Funding for this research was provided by:

Agencia Nacional de Investigación y Desarrollo (1181645, 1221745, NCN2023_32, 13220203 explorador, 21151265, 21151265, 1151293)

UNAB (DI-06-24/REG)

National Institute of Mental Health and Neurosciences (R01-EY014074, R01-638 EY014420)
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Text and Data Mining valid from 2024-10-25

Version of Record valid from 2024-10-25
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Article History

Received: 26 May 2024

Accepted: 24 September 2024

First Online: 25 October 2024

Declarations

:

: All experiments conducted in mice were handled according to the guidelines for the handling and care of experimentation established by the NIH (NIH, Maryland, USA) and following the protocol approved by the bioethics committee of Andres Bello University (approval certificate 014/2017).

: Not applicable.

: We declare no competing interests.

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