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Mutation on JmjC domain of UTX impaired its antitumor effects in pancreatic cancer via inhibiting G0S2 expression and activating the Toll-like signaling pathway

Crossref DOI link: https://doi.org/10.1186/s10020-024-01023-2

Published Online: 2024-12-20

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Shen, Xiao-hua

Xiong, Shu-ping

Wang, Sheng-peng

Lu, Shan

Wan, Yi-ye

Zhang, Hui-qing
Funding

Funding for this research was provided by:

Jiangxi Science Fund for Distinguished Young Scholars (20212ACB216012)

Funding Program for Academic and Technical Leaders of Main Subjects in Jiangxi Province (20213BCJ22009)
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Text and Data Mining valid from 2024-12-20

Version of Record valid from 2024-12-20
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Article History

Received: 2 August 2024

Accepted: 2 December 2024

First Online: 20 December 2024

Declarations

:

: All the patients signed an informed consent in this research. This research was approved by the Ethics Review Committee of Jiangxi Cancer Hospital. The animal experiments were conducted by the “Guiding Principles in the Care and Use of Animals” (China) and approved by Jiangxi Cancer Hospital (the approval number: 2021ky034).

: All authors had access to the study data and have reviewed and approved the final manuscript for publication.

: The authors declare no competing interests.

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