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Authors
Gil-Korilis, Adrián https://orcid.org/0009-0001-0614-1168
Ergui-Arbizu, Jorge https://orcid.org/0009-0003-2583-4538
Hanák, Petr https://orcid.org/0000-0002-2156-592X
Danešová, Natálie https://orcid.org/0009-0000-9757-2141
Tomášová, Kristýna https://orcid.org/0000-0002-8080-6666
Valíčková, Anna https://orcid.org/0000-0001-7101-5742
Horák, Josef https://orcid.org/0000-0003-2688-4273
Gentiluomo, Manuel https://orcid.org/0000-0002-0366-9653
Levý, Miroslav https://orcid.org/0000-0003-3321-6644
Křivonosková, Soňa
Král, Jan https://orcid.org/0000-0001-6960-1013
Jungwirth, Jiří
Vodičková, Ludmila https://orcid.org/0000-0002-8277-539X
Vymetálková, Veronika https://orcid.org/0000-0001-6870-6788
Azqueta, Amaya https://orcid.org/0000-0003-4857-9931
Campa, Daniele https://orcid.org/0000-0003-3220-9944
Vodička, Pavel https://orcid.org/0000-0003-2376-1243
Vodenková, Soňa https://orcid.org/0000-0003-0315-5668
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Funding
Funding for this research was provided by:
National Institute for Cancer Research (LX22NPO5102)
Ministry of Health of the Czech Republic in cooperation with the Czech Health Research Council (NU22J-03-00033)
Grantová Agentura České Republiky (GX21-04607X)
Grantová Agentura České Republiky (G22-05942S)
Charles University Czech Republic (540225)
Cooperatio Program
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Article History
Received: 17 September 2025
Accepted: 14 January 2026
First Online: 21 February 2026
Declarations
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: All study participants signed a written consent to participate in the study and approved the use of their biological samples for genetic analyses. This study was conducted in compliance with the principles laid out in the World Medical Association Declaration of Helsinki and the Department of Health and Human Services Belmont Report. Participant information was coded to protect their identity. The inclusion of study participants was approved by the Ethics Committee of the Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic, and the Ethics Committee of the Institute for Clinical and Experimental Medicine and Thomayer University Hospital, Prague, Czech Republic (for CRC patients: Docket No. 06366/23 + 15408/23, A-23–07; Docket No. 1004/16, G-16–06-38; Docket No. 786/09, G-09–04-09; protocol G-14–08-67) (for healthy individuals: Docket No. 6799/21, G-20–55; protocol G-17–03-02).
: Not applicable.
: The authors declare no competing interests.
