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Authors
Zhao, Lina
Dong, Shuoyan
Tang, Qin
Liu, Jie
Cui, Qian
Wang, Hongyan
Zhang, Ying
Li, Peng
Li, Deqiang
Wang, Yunying
Shi, Hui
Wu, Hening
Meng, Yu
Gao, Ying
Xie, Keliang
Yang, Fei
Li, Yun
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (82302413)
Joint Funds of the Natural Science Foundation of Tianjin (25JCLMJC00350)
Tianjin Key Research and Development Program International Science and Technology Cooperation Project (25YFGKHZ00160 to KX)
Tianjin Key Medical Discipline Construction Project (TJYXZDXK-3-006C)
Tianjin Health Research Project (TJWJ2024QN006)
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Article History
Received: 30 June 2026
Accepted: 17 August 2026
First Online: 28 August 2026
Declarations
Ethics approval and consent to participate: The study protocol was approved by the Institutional Review Board of Tianjin Medical University General Hospital (approval no.IRB2022-YX-222–01) and was prospectively registered with the Chinese Clinical Trials Registry (ChiCTR2200067084). The recruitment period for this study was from October 2024 to September 2025. Written informed consent was obtained from all participants or their legally authorized representatives before enrollment.
Consent for publication: All participants (or their legal guardians/representatives) involved in this study provided written informed consent for publication, including the use of de-identified data and any potentially identifiable materials (e.g., clinical images, genetic data, or case details).
Competing interests: The authors declare no competing interests.
