Updates are available Correction dated 2019-01-07

Article History

Received: 10 August 2018

Accepted: 3 October 2018

First Online: 19 October 2018

Change Date: 7 January 2019

Change Type: Correction

Change Details: Following publication of the original article [1], the authors notified us that a part of the Figure 3 legend was omitted during proofing stage.

Ethics approval and consent to participate

: Investigators obtained local ethics committee approval of the protocol, which was registered at ClinicalTrials.gov (NCT02686034).

: Not applicable.

: <b>L. Grazzi</b> has received consultancy and advisory fees from Allergan S.p.A. and electroCore, Inc. <b>C. Tassorelli</b> has consulted for Allergan S.p.A.; electroCore, Inc.; Eli Lilly and Company; and Novartis AG and has received research grants from the European Commission and the Italian Ministry of Health. She is also a principal investigator or collaborator for RCTs sponsored by Alder BioPharmaceuticals Inc.; Eli Lilly and Company; and Teva Pharmaceutical Industries Ltd. <b>M. de Tommaso</b> has received advisory fees from Allergan S.p.A.; Neopharmed; and Pfizer Inc. <b>G. Pierangeli</b> has nothing to disclose. <b>P. Martelletti</b> has received research grants, advisory board fees, or travel fees from ACRAF; Allergan S.p.A.; Amgen Inc.; electroCore, Inc.; Novartis AG; and Teva Pharmaceutical Industries Ltd. <b>I. Rainero</b> has received consultancy fees from electroCore, Inc., and Mylan N.V. and research grants from the European Commission -- Horizon 2020. He is also a principal investigator for RCTs sponsored by Axovant Sciences Ltd. and TauRx Pharmaceuticals Ltd. <b>P. Geppetti</b> has received consultancy fees from Allergan S.p.A.; electroCore, Inc.; Evidera; Novartis AG; Pfizer Inc.; and Sanofi S.p.A. and research grants from Chiesi Farmaceutici S.p.A. He is also a principal investigator for RCTs sponsored by Eli Lilly and Company; Novartis AG; and Teva Pharmaceutical Industries Ltd. <b>A. Ambrosini</b> has received consultancy fees from Almirall, S.A., and travel grants from Allergan S.p.A.; Almirall, S.A.; and Novartis AG. <b>P. Sarchielli</b> has received clinical study fees from Allergan S.p.A. <b>E. Liebler</b> is an employee of electroCore, Inc., and receives stock ownership. <b>P. Barbanti</b> has received consultancy fees from Allergan S.p.A.; electroCore, Inc.; Janssen Pharmaceuticals, Inc.; Lusofarmaco; and Visufarma and advisory fees from Abbott Laboratories and Merck & Co., Inc.

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