Updates are available Correction dated 2018-12-18

Article History

Received: 9 August 2018

Accepted: 3 October 2018

First Online: 1 November 2018

Change Date: 18 December 2018

Change Type: Correction

Change Details: Following publication of the original article [1], the authors notified us o that the Table 1 citation within the legend was not presented as initially requested.

Ethics approval and consent to participate

: Investigators obtained local ethics committee approval of the protocol, which was registered at ClinicalTrials.gov (NCT02686034). All patients provided written informed consent in advance of study participation.

: Not applicable.

: P. Martelletti has received research grants, advisory board fees, or travel fees from ACRAF; Allergan S.p.A.; Amgen Inc.; electroCore, Inc.; Novartis AG; and Teva Pharmaceutical Industries Ltd.L. Grazzi has received consultancy and advisory fees from Allergan S.p.A. and electroCore, Inc.G. Pierangeli has nothing to disclose.I. Rainero has received consultancy fees from electroCore, Inc., and Mylan N.V. and research grants from the European Commission – Horizon 2020. He is also a principal investigator for RCTs sponsored by Axovant Sciences Ltd. and TauRx Pharmaceuticals Ltd.P. Geppetti has received consultancy fees from Allergan S.p.A.; electroCore, Inc.; Evidera; Novartis AG; Pfizer Inc.; and Sanofi S.p.A. and research grants from Chiesi Farmaceutici S.p.A. He is also a principal investigator for RCTs sponsored by Eli Lilly and Company; Novartis AG; and Teva Pharmaceutical Industries Ltd.A. Ambrosini has received consultancy fees from Almirall, S.A., and travel grants from Allergan S.p.A., Almirall, S.A., and Novartis.P. Sarchielli has received clinical study fees from Allergan S.p.A.P. Barbanti has received consultancy fees from Allergan S.p.A.; electroCore, Inc.; Janssen Pharmaceuticals, Inc.; Lusofarmaco; and Visufarma and advisory fees from Abbott Laboratories; Merck & Co., Inc.; Novartis AG; and Teva Pharmaceutical Industries Ltd. He is also a principal investigator for RCTs sponsored by Alder BioPharmaceuticals Inc.; Eli Lilly and Company; GlaxoSmithKline Pharmaceuticals Ltd.; and Teva Pharmaceutical Industries Ltd.C. Tassorelli has consulted for Allergan S.p.A.; electroCore, Inc.; Eli Lilly and Company; and Novartis AG and has received research grants from the European Commission and the Italian Ministry of Health. She is also a principal investigator or collaborator for RCTs sponsored by Alder BioPharmaceuticals Inc.; Eli Lilly and Company; Novartis; and Teva Pharmaceutical Industries Ltd.E. Liebler is an employee of electroCore, Inc., and receives stock ownership.M. de Tommaso has received advisory fees from Allergan S.p.A.; Neopharmed; and Pfizer Inc.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.