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Article History

Received: 20 December 2019

Accepted: 10 August 2020

First Online: 24 August 2020

Ethics approval and consent to participate

: All mice were euthanized by experts via cervical dislocation or using carbon dioxide from a commercially supplied tank, and every effort was made to minimize their suffering. This study was performed in strict accordance with the recommendations in the Fundamental Guidelines for Proper Conduct of Animal Experiment and Related Activities in Academic Research Institutions published by the Ministry of Education, Culture, Sports, Science and Technology of Japan, and all procedures were conducted in accordance with the Regulation of Animal Experiments in Chubu University, Osaka University and Yamagata University. The protocol was approved by the Institutional Animal Care and Use Committees of Chubu University (approval number 3010004), Osaka University (approval number H25–02-0) and Yamagata University (approval number 26–104).

: Not applicable. The manuscript does not contain data from any individual person.

: The authors declare that they have no competing interests.