Chen, Changshun https://orcid.org/0009-0002-6449-0582
Gu, Jinyi
Yang, Chenhui
Yang, Fei
Liu, Zirui
Wen, Lei
Chen, Rongjing
Geng, Bin
Xia, Yayi
Funding for this research was provided by:
National Natural Science Foundation of China (82060405)
National Natural Science Foundation of China (82360436)
Natural Science Foundation of Gansu Province (22JR5RA943、22JR5RA956)
Natural Science Foundation of Gansu Province (24YFFA043)
Natural Science Foundation of Gansu Province (23JRRA1500)
Lanzhou Science and Technology Plan Program (2021-RC-102)
Cuiying Scientific and Technological Innovation Program of Lanzhou University Second Hospital (CY2021-MS-A07)
Cuiying Scientific and Technological Innovation Program of Lanzhou University Second Hospital (CY2022-MS-A19)
Article History
Received: 15 May 2025
Accepted: 24 November 2025
First Online: 6 January 2026
Declarations
:
: The study protocol was performed in accordance with the Declaration of Helsinki, and written informed consent was obtained from all participants. The study protocol was approved by the Medical Ethics Committee of the Second Hospital of Lanzhou University (approval no. 2024 A-1265), approved on 10 October 2024.All animal procedures were conducted following the recommendations of the International Council for Laboratory Animal Science (ICLAS) guidelines. All experimental designs and protocols involving animals were approved by the Animal Care Committee of the Second Hospital of Lanzhou University (approval no. D2024-920) on 8 October 2024.
: All authors gave their consent for publication.
: The authors declare no competing interests.