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Keratinization-related gene signature predicting survival and response to radiation in patients with HPV-negative head and neck squamous cell carcinoma via regulation of cornification and integrin signaling

Crossref DOI link: https://doi.org/10.1186/s11658-025-00855-y

Published Online: 2026-01-29

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lee, Min Kyeong

Joo, Harim

Bae, Minji

Lee, Yeonseo

Noh, Joo-Kyung

Lee, Young Chan

Lee, Jung Woo

Min, Soonki

Kong, Moonkyoo

Ko, Seong-Gyu

Eun, Young-Gyu
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Text and Data Mining valid from 2026-01-29

Version of Record valid from 2026-02-20
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Article History

Received: 30 June 2025

Accepted: 17 December 2025

First Online: 29 January 2026

Declarations

:

: All experimental protocols were approved by the Kyung Hee Medical Center Institutional Animal Care and Use Committee (KHMC-IACUC-23–003-02). All methods were carried out in accordance with relevant guidelines and regulations, and the study was conducted in compliance with the ARRIVE guidelines. The local ethics committee operates in accordance with the principles and guidelines of the International Council for Laboratory Animal Science (ICLAS).

: Not applicable.

: The authors declare that they have no competing interests.

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