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TRMT6/TRMT61A-mediated tRNA m1A modification enhances protein translation and activates the IRE1α–XBP1s pathway to promote anaplastic thyroid cancer progression

Crossref DOI link: https://doi.org/10.1186/s11658-026-00863-6

Published Online: 2026-02-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ding, Ying

Feng, Ziyang

Chen, Guanjun

Liu, Yunqing

Zhu, Yuxing

Cao, Ke
Funding

Funding for this research was provided by:

China Postdoctoral Science Foundation (2024M763707)

National Natural Science Foundation of China (82403854)

National Natural Science Foundation of China (82473260)
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Text and Data Mining valid from 2026-02-10

Version of Record valid from 2026-03-16
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Article History

Received: 21 July 2025

Accepted: 19 January 2026

First Online: 10 February 2026

Declarations

:

: Informed consent was obtained from all participants, and the study was approved by the Ethics Committee of Xiangya Hospital, Central South University, on April 19, 2020 (approval number: 202004192), in accordance with the principles of the Declaration of Helsinki. All animal experiments were approved by the Institutional Animal Care and Ethics Committee of Central South University, on March 21, 2025 (approval number: APU-2025-0093). The Local Ethics Committee operates in accordance with the guidelines of the International Council for Laboratory Animal Science.

: All authors have agreed with publishing this manuscript.

: The authors declare no competing interests.

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