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Article History

Received: 13 July 2025

Accepted: 5 February 2026

First Online: 14 March 2026

Declarations

:

: The project was conducted in compliance with the guidelines outlined in the Declaration of Helsinki and the Basel Declaration. Studies involving human tissues were approved by the Ethics Committee of Jiangnan University Medical Center (permission number: Ethics Review No. Y-125; date issued: 15 January 2021). The study was performed in accordance with the principles of the Declaration of Helsinki. The animal experiments were performed in accordance with the Basel Declaration and were approved by the Animal Ethics Committee of Jiangnan University (permission number: JN20211215c0500630; date issued: 15 December 2021). The ethics committee follows the guidelines of the International Council for Laboratory Animal Science (ICLAS) to ensure the ethical compliance of the experiments.

: The manuscript has been approved by all the authors.

: The authors declare no competing interests.