Liu, Zhen
He, Mei
Luo, Xuan
Pan, Hu
Hu, Juanli
Wan, Zhengqing
Peng, Yin
Luo, Yixiao
Wang, Hua
Mao, Xiao
Funding for this research was provided by:
Hunan Provincial Maternal and Child Health Care Hospital Postdoctoral Research Startup Fund
The National Key Research and Development Program of China (No.2021YFC1005300)
Clinical Medical Research Center For Hereditary Birth Defects and Rare Diseases In Hunan Province (No. 2023SK4053)
the Major Scientific and Technological Projects for Collaborative Prevention and Control of Birth Defects in Hunan Province, China (No. 2019SK1010, 2019SK1014)
Natural Science Foundation of Hunan Province, China (No.2022JJ40206)
Article History
Received: 2 July 2024
Accepted: 17 June 2025
First Online: 12 July 2025
Declarations
:
: This study was conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Board (IRB) of Hunan Provincial Maternal and Child Health Care Hospital. Written informed consent was obtained from the legal guardians of all participants involved in the study. The consent covered all facets of participation and data utilization. To ensure the protection of our patient’s and control subjects’ privacy, all personal identifiers were removed from the study data.
: We hereby clarify that written informed consent for the publication of their personal or clinical details, along with any identifying images, has been obtained from all participants involved in the study. For minor patient, written informed consent has been obtained from his parents. This consent encompasses the use of these details and images in this study and any potential publication in scientific journals.
: The authors declare no competing interests.