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Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology

Crossref DOI link: https://doi.org/10.1186/s12263-017-0576-0

Published Online: 2017-09-06

Published Print: 2017-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Miousse, Isabelle R.

Pathak, Rupak

Garg, Sarita

Skinner, Charles M.

Melnyk, Stepan

Pavliv, Oleksandra

Hendrickson, Howard

Landes, Reid D.

Lumen, Annie

Tackett, Alan J.

Deutz, Nicolaas E.P.

Hauer-Jensen, Martin

Koturbash, Igor http://orcid.org/0000-0002-4090-7008
Funding

Funding for this research was provided by:

National Institute of General Medical Sciences (1P20GM109005)

Arkansas Space Grant Consortium (NNX13AB29A)
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Article History

Received: 1 March 2017

Accepted: 28 August 2017

First Online: 6 September 2017

Ethics approval

: This study was performed according to the principles and guidelines of the National Institute of Health Guide for the Care and Use of Laboratory Animals. All treatment and testing procedures were approved by the Animal Care and Use Committee of the University of Arkansas for Medical Sciences, USA.

: Not applicable.

: The authors declare that they have no competing interests.

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