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Association of non-alcoholic fatty liver polygenic risk scores with the incident and progressive non-alcoholic fatty liver disease in Chinese population

Crossref DOI link: https://doi.org/10.1186/s12263-025-00779-4

Published Online: 2025-10-31

Published Print: 2025-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhou, Yang

Zhou, Di

Chen, Shuohua

Yang, Chenlu

Wu, Shutong

Wang, Xiaomo

Lan, Yanqi

Lu, Ying

Zhou, Mengge

Wu, Shouling

Li, Man

Wang, Li
Funding

Funding for this research was provided by:

Noncommunicable Chronic Diseases-National Science and Technology Major Project (2023ZD0508705)

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China (82370593)

Beijing Municipal Health Commission Capital Health Development Research Project (2022-1-2021)
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Text and Data Mining valid from 2025-10-31

Version of Record valid from 2025-10-31
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Article History

Received: 2 May 2025

Accepted: 6 September 2025

First Online: 31 October 2025

Declarations

:

: This study was based on a nested case–control design within the Kailuan cohort and was registered in the Chinese Clinical Trial Registry (registration number: ChiCTR-TNRC-11001489). The study was conducted in accordance with the Declaration of Helsinki and approved by the Ethics Committees of Kailuan General Hospital and the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences. Written informed consent was obtained from all participants prior to their inclusion in the study.

: All authors declare that they have no competing financial interests or personal relationships that could influence the work reported in this paper.

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