Yang, Chenxin
Huangfu, Mingxuan
Dai, Xintong
Liu, Lumeng
Zhao, Huifang
Yuan, Yu
Zhang, Chunze
He, Tao
Shan, Changliang
Wang, Xiangling
Zhang, Shuai
Funding for this research was provided by:
National Natural Science Foundation of China (82305332)
National Natural Science Foundation of China (82273963)
Natural Science Foundation of Tianjin (25JCLMJC00190)
Natural Science Foundation of Tianjin (24JCZDJC00770)
Article History
Received: 13 January 2026
Accepted: 28 April 2026
First Online: 12 May 2026
Declarations
:
: The animal study protocol was approved by the Laboratory Animal Ethics Committee Nankai University (protocol code: 2021-SYDWLL-000069). Tumor tissues were obtained from CRC patients during surgery, which provided by Tianjin Union Medical Center (Tianjin, China). The study was conducted in accordance with the Declaration of Helsinki and approved by the Requirements of the Ethical Review System of Biomedical Research Involving Human by National Health and Family Planning Commission of China, Nankai University and Tianjin Union Medical Center Ethics Committee (protocol code: NKUIRB2021022). Informed consent was obtained from all subjects involved in the study.
: Not applicable.
: The authors declare no competing interests.