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Article History

Received: 11 April 2018

Accepted: 27 December 2018

First Online: 19 January 2019

Ethics approval and consent to participate

: All animal studies were performed in compliance with the Dutch law on animal experimentation (Wet op dierproeven, Wod / Directive 2010/63/EU of the European parliament and of the council of 22 September 2010 on the protection of animals used for scientific purposes). The study design was authorized by the Technical Committee of the SKV (Foundation for Quality Guarantee Veal Sector) on the 4th of February 2015, document TC15. Animals were placed under regular agricultural care according to the regulations of the Integrated Chain Management System (IKB) and regular clinical veterinary practices according to the general rules laid down in Council Directive 98/58/EC. Animal transport and handling during transport was compliant to EU directive 1/2005/EG and 1255/97/EG.

: All authors of the manuscript have read and agreed to its content and are accountable for all aspects of the accuracy and integrity of the manuscript in accordance with ICMJE criteria.

: TNO is an independent non-profit research organization (employer of BK, TvdB, RM, VA, MC, MH, and ES) and has previously received grants from SKV. Ducares (employer of DM, MvB and AvdB) is a spin off company of TNO, and provides fee for service in biochemical analysis to both TNO and SKV. TNO holds a minority share in the company. <i>Stichting Kwaliteitsgarantie Vleeskalversector</i> (SKV) is an independent foundation, aiming to support for safe and responsibly produced veal.

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