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Article History

Received: 11 March 2021

Accepted: 6 July 2021

First Online: 4 August 2021

Declarations

:

: All relevant ethical regulations were followed in this study. An informed consent was obtained from the human subjects. The collection and analysis of patient samples was approved by the ethics committee of Northern Switzerland (EKNZ, Study ID: 310/12/PB_2019-00154/Genetische Analyse des Leberzellkarzinoms). Samples collected after 2016 were obtained under a written consent by the patient. Before 2016, samples were included if no active refusal of the patient existed, which was approved by the ethics committee. The animal license number was 2555. For two samples, we had no refusal from the patient to use the tissue for research purpose and because the tissue derived from 1999 and 2002 only an approval from the Ethics committee (EKNZ, Basel Switzerland) was needed at that time by the Swiss regulation to use the tissue for research purpose. For all remaining samples, a written informed consent of the patient was present to use the tissue for research purposes, as well as an approval from the Ethics committee (EKNZ, Basel Switzerland).

: Not applicable

: There is no financial or non-financial competing interest.