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A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency

Crossref DOI link: https://doi.org/10.1186/s12864-025-11386-3

Published Online: 2025-02-26

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lukasiak, Sebastian

Kalinka, Alex

Gupta, Nikhil

Papadopoulos, Angelos

Saeed, Khalid

McDermott, Ultan

Hannon, Gregory James

Ross-Thriepland, Douglas

Walter, David
License Information

Text and Data Mining valid from 2025-02-26

Version of Record valid from 2025-02-26
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Article History

Received: 6 December 2024

Accepted: 19 February 2025

First Online: 26 February 2025

Declarations

:

: Not applicable.

: Not applicable.

: SL, AP, UM, and DRT are employees of AstraZeneca. AK, NG, KS and DW are employees of Cancer Research Horizons.

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