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Article History

Received: 10 December 2024

Accepted: 11 March 2025

First Online: 24 March 2025

Declarations

:

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study. All animal experiments were conducted in accordance with the guidelines of the Guangdong Provincial People’s Hospital Animal Care and Use Committee and were approved under the ethical approval number KY2023-519-02. The guidelines from Directive 2010/63/EU of the European Parliament on the protection of animals used for scientific purposes and the NIH Guide for the Care and Use of Laboratory Animals were strictly followed to ensure the welfare of the animals.

: Informed consent was obtained from all individual participants included in the study. The authors affirm that human research participants provided informed consent for publication of the images in Figure(s) 1a, and 1b.

: The authors declare no competing interests.