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Single-cell transcriptomic and chromatin accessibility atlas of peripheral blood mononuclear cells reveals immune cell heterogeneity and breed-specific characteristics in Duroc and Meishan pigs

Crossref DOI link: https://doi.org/10.1186/s12864-026-12854-0

Published Online: 2026-04-25

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Fan, Hairui

Du, Cui

Xu, Chao

Wang, Haifei

Wang, Yejun

Wu, Zhengchang

Zhao, Bin

Chen, Chao

Shang, Shaobin

Sun, Ming-an

Bao, Wenbin
Funding

Funding for this research was provided by:

National Key Research and Development Program of China (2023YFF1000900)
License Information

Text and Data Mining valid from 2026-04-25

Version of Record valid from 2026-06-09
More Information

Article History

Received: 21 November 2025

Accepted: 8 April 2026

First Online: 25 April 2026

Declarations

:

: All experiments were approved by the Animal Care and Use Committee of Yangzhou University (license approval number: SYXK (Su) 2021-0026). Before the project began, informed consent was obtained from all relevant personnel. The 10x multiome data of human PBMCs was downloaded from the 10x genomics website: .

: All authors have read the journal’s position on issues involved in ethical publication, and all authors have approved the final version of the manuscript.

: The authors declare no competing interests.

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