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Systematic evaluation of single-cell foundation model interpretability: attention-derived edge scores add no incremental value over gene-level features for perturbation-target prediction

Crossref DOI link: https://doi.org/10.1186/s12864-026-12965-8

Published Online: 2026-07-22

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kendiukhov, Ihor
Funding

Funding for this research was provided by:

Eberhard Karls Universität Tübingen
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Text and Data Mining valid from 2026-07-22

Version of Record valid from 2026-07-22
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Article History

Received: 10 March 2026

Accepted: 14 May 2026

First Online: 22 July 2026

Declarations

Ethical approval and consent to participate: Not applicable. This study used only publicly available, de-identified single-cell transcriptomic datasets. No new human or animal data were generated.

Consent for publication: Not applicable.

Competing interests: The authors declare no competing interests.

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