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Zebrafish mecp2 null-mutation increases anxiety and cortisol levels but no change in adult social preference and larval chemically-induced hyperlocomotion

Crossref DOI link: https://doi.org/10.1186/s12868-025-00946-8

Published Online: 2025-07-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Shams, Soaleha https://orcid.org/0000-0003-4033-2539
Cronell, Pierre

Landin, Jenny

Pietri, Thomas https://orcid.org/0000-0002-9536-8363
Gimdal, Adrian Ekehorn

Kettunen, Petronella https://orcid.org/0000-0002-2510-3423
Westberg, Lars https://orcid.org/0000-0003-3794-3910
Funding

Funding for this research was provided by:

Stiftelserna Wilhelm och Martina Lundgrens

Natural Sciences and Engineering Research Council of Canada (PDF-546008-2020)

Adlerbertska Stiftelserna

Health and Medical Care Committee of the Regional Executive Board, Region Västra Götaland (ALF-GBG-724331, ALF-GBG-721481, ALF-GBG-624141)

Gunvor och Josef Anérs Siftelse

Carl Tryggers Stiftelse för Vetenskaplig Forskning

Alzheimerfonden,Sweden

Svenska Forskningsrådet Formas

Stiftelsen Längmanska Kulturfonden

Stiftelsen Psykiatriska Forskningsfonden,Sweden

Wenner-Gren Stiftelserna

Åhlén-stiftelsen

Vetenskapsrådet (2018-02904, 2022-00863)

Hjärnfonden

University of Gothenburg
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Article History

Received: 18 October 2024

Accepted: 20 March 2025

First Online: 1 July 2025

Declarations

:

: Experiments adhered strictly to a study protocol approved by the local animal ethics committee in Gothenburg and followed the animal use and care guidelines of the Swedish National Board for Laboratory Animals (Ethical permit # 5.8.18–08496/2018) and European Directive 2010/63/EU.

: Not applicable.

: The authors declare no competing interests.

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