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Authors
Kan, Liyen K.
Drill, Matthew
Muscat, Andrea
Sanfilippo, Paul
Sequeira, Richard P.
Jayakrishnan, Padmakrishnan C.
Vo, Anh
Wong, Nicholas C.
Todaro, Marian
McLean, Catriona
Drummond, Katherine J.
Hunn, Martin
Williams, David A.
O’Brien, Terence J.
Monif, Mastura
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Funding
Funding for this research was provided by:
National Health and Medical Research Council (2011590)
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Article History
Received: 12 March 2024
Accepted: 14 August 2025
First Online: 1 October 2025
Declarations
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: Protocols for obtaining and handling human brain tissue were reviewed and approved by the Human Research Ethics Committees (HREC) of the RMH (HREC 2006.119) and The Alfred (HREC 2017.450). Written informed consent was obtained from all patients or their corresponding legally authorised representatives.
: Not applicable.
: TO has received support from the National Health and Medical Research Council, The National Institute of Neurological Disorders and Stroke and Monash University. He has been supported by research grants and consultancies to his institution from Eisai, UCB Pharma, Praxis Precision Medicines, BioGen and Supernus.MM has served on advisory board for Merck, Biogen, and Novartis. She has received speaker honoraria from Merck and Biogen. Her institution receives funding from Merck, Australian National Health Medical Research Council and MS Research Australia.
: MM has served on advisory board for Merck, Biogen, and Novartis. She has received speaker honoraria from Merck and Biogen. Her institution receives funding from Merck, Australian National Health Medical Research Council and MS Research Australia.
