Document is current

Article History

Received: 17 September 2019

Accepted: 29 December 2019

First Online: 20 January 2020

Ethics approval and consent to participate

: All research was approved by the institutional review board of Jiangxi maternal and child health hospital, Nanchang, China. Written informed consents for the use of medical information and genetic analysis were obtained from all the enrolled subjects.

: The enrolled adults provided signed consents for the permission of using their clinical information and sequencing data for research purposes and/or scientific publications. For the participants under 16 years old, written informed consent was obtained from their parents. For the participant died at adult stage (I:2), written informed consent was obtained from her daughters.

: The authors declare that they have no competing interests.