Hiraiwa, Hiroaki https://orcid.org/0000-0002-1606-7037
Nagai, Shin
Ito, Ryota
Kondo, Kiyota
Kazama, Shingo https://orcid.org/0009-0009-2867-4756
Kondo, Toru https://orcid.org/0000-0001-6853-7574
Adachi, Shiro https://orcid.org/0000-0001-8924-1916
Furusawa, Kenji
Tanaka, Akihito https://orcid.org/0000-0003-2260-1942
Morimoto, Ryota https://orcid.org/0000-0003-0931-3188
Okumura, Takahiro https://orcid.org/0000-0001-5076-2052
Murohara, Toyoaki https://orcid.org/0000-0003-2723-6243
Funding for this research was provided by:
Konica Minolta, Inc.
Konica Minolta Science and Technology Foundation
Kowa Life Science Foundation
Suzuken Memorial Foundation
The Nitto Foundation
Kondou Kinen Medical Foundation
The Hori Sciences and Arts Foundation
Chukyo Longevity Medical and Promotion Foundation
Article History
Received: 11 December 2024
Accepted: 2 May 2025
First Online: 19 May 2025
Declarations
:
: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of Nagoya University Hospital (Date: 30 June 2023/No. 2023/0103). Written informed consent for participation was obtained from all individual participants included in the study.
: Not applicable.
: H.H. has received research grants from Konica Minolta, Inc., Konica Minolta Science and Technology Foundation, Kowa Life Science Foundation, Suzuken Memorial Foundation, The Nitto Foundation, Kondou Kinen Medical Foundation, The Hori Sciences and Arts Foundation, and Chukyo Longevity Medical and Promotion Foundation. T.K. has received lecture fees from AstraZeneca K.K., Boehringer Ingelheim, Ono Pharmaceutical Co., Ltd., Kowa Company, Ltd., and Novartis Pharma K.K. that were not associated with this work. T.O. has received research grants from Pfizer Japan, Alnylam Japan Pharmaceuticals, and Alexion Pharmaceuticals; has received lecture fees from Pfizer Japan, Novartis Pharma, AstraZeneca, and Boehringer Ingelheim that were not connected to this work; and is affiliated with a department sponsored by Medtronic Japan. T.M. has received an unrestricted research grant from the Department of Cardiology, Nagoya University Graduate School of Medicine, from Astellas Pharma Inc., Daiichi-Sankyo Co. Ltd., Dainippon Sumitomo Pharma Co. Ltd., Kowa Co. Ltd., MSD K.K., Mitsubishi Tanabe Pharma Co., Nippon Boehringer Ingelheim Co. Ltd., Novartis Pharma K.K., Otsuka Pharma Ltd., Pfizer Japan Inc., Sanofi-Aventis K.K., Takeda Pharmaceutical Co. Ltd., and Teijin Pharma Ltd. The other authors declare that they have no conflicts of interest associated with this manuscript.