Gaskell, Charlotte
Linton, Kim
Bishton, Mark
McIlroy, Graham
Lax, Siân
Fox, Sonia
Hopkins, Louise
Collings, Rebecca
Rhodes, Malcolm
Seale, Tania
Jackson, Aimee
Article History
Received: 20 December 2024
Accepted: 18 April 2025
First Online: 3 May 2025
Declarations
:
: The REFRACT protocol has been approved by the UK (London—Fulham Research Ethics Committee on 22-Jun-2023); current version 2.0, 03-May-2023. Competent Authority approval was granted in the UK by the Medicines and Healthcare Products Regulatory Agency (MHRA) on 01-Jun-2023.All patients provide written informed consent to participate.
: Not applicable.
: MB: Honoraria from Abbvie, Roche, Celltrion and Gilead. Consulting or advisory role for Incyte, Roche, Lilly and Abbvie, Research funding from Roche and Takeda. Travel expenses from Roche. All other authors declare no competing interests.