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Authors
Krastman, Patrick
Heijneman, Kimberley
Bosman, Angeline
de Wilde, Marcel
van der Lei, Johan
Runhaar, Jos
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Article History
Received: 31 October 2025
Accepted: 19 May 2026
First Online: 23 May 2026
Declarations
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: The study was conducted in accordance with the Declaration of Helsinki and approved by the IPCI scientific and ethical advisory board (nr 9/2024). As the IPCI database contains observational data, the study was not subject to the Medical Research Involving Human Subjects Act (WMO) and did not require medical ethics committee approval [ ]. GPs whose data are linked to IPCI are required to inform their patients about the use of their de-identified data for medical research. Patients can object to the use of their data and if this is the case, the data of these patients are not included in the research datasets.
: Not applicable.
: The authors declare no competing interests.
