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Article History

Received: 2 June 2019

Accepted: 20 August 2019

First Online: 27 August 2019

Ethics approval and consent to participate

: Written informed consent for clinical and laboratory data acquisition and analysis was obtained from each patient at entry into the study. Data acquisition and evaluation was approved by the local ethics committee of Heidelberg University (S-043/2011) and conformed to the ethical guidelines of the Declaration of Helsinki, as reflected in an a priori approval by the institution’s human research review committee.

: Not applicable.

: The authors declare that they have no competing interests.