Osawa, Yosuke http://orcid.org/0000-0003-3581-1009
Yoshio, Sachiyo
Aoki, Yoshihiko
Korenaga, Masaaki
Imamura, Masatoshi
Oide, Takashi
Okawara, Miku
Kawai, Hironari
Tsutsui, Yuriko
Yoshida, Yuichi
Yoshikawa, Shiori
Mori, Taizo
Yamazoe, Taiji
Kanto, Tatsuya
Funding for this research was provided by:
National Center for Global Health and Medicine (30-shi-2001, 20A1002, 30-shi-1011)
Japan Agency for Medical Research and Development (19fk0210058h0001, 20fk0210058h0002)
Takeda Science Foundation
Article History
Received: 28 September 2020
Accepted: 27 January 2021
First Online: 8 February 2021
Ethics approval and consent to participate
: All analyses using human samples were approved by the institutional research ethics committee at NCGM Kohnodai Hospital (NCGM-G-001967-04 and NCGM-G-003231-00). Written informed consent was obtained from all patients. All animal experiments were conducted in accordance with institutional guidelines (Guide for the Care and Use of Laboratory Animals prepared by the National Academy of Sciences), act on welfare and management of animals (Act No. 46 of May 30, 2014, Japanese low), and standards relating to the care and keeping and reducing pain of laboratory animals (notice of the Japanese ministry of the environment, NO88 of 2006) and the protocol was approved by the Animal Research Committee of the National Center for Global Health and Medicine (Nos. 20555 and 20056).
: Not applicable.
: Tatsuya Kanto received honoraria from Gilead Sciences, MSD, and Abbie.