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Authors
Liu, Huan
Wu, Huisheng
Tang, Lili
Zhao, Yangxi
Shi, Yunping
Zhang, Sichen
Fang, Quan
Fan, Yinguang
Liu, Xuesheng
Guo, Peipei
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Funding
Funding for this research was provided by:
Research Fund Project of Anhui Medical University (2022xkj140 and 2022xkj148)
Research Fund Project of Anhui Medical University (2022xkj140 and 2022xkj148)
Anhui Institute of Translational Medicine (2023zhyx-C61)
Science Research Fund of Colleges and Universities in Anhui Province of China (2022AH051187)
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Article History
Received: 17 July 2025
Accepted: 4 December 2025
First Online: 16 December 2025
Declarations
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: This study was approved by the Ethics Committee of the First Affiliated Hospital of Anhui Medical University (Approval No. PJ2022-01-10). Prior to patient enrollment, the trial was registered with the Chinese Clinical Trial Registry (ChiCTR2100053388; , registered on November 20, 2021). The study adhered to the CONSORT guidelines and was conducted in accordance with the principles of the Declaration of Helsinki. Written informed consent was obtained from all participants prior to enrolment.
: Not applicable.
: The authors declare no competing interests. The authors certify that there is no conflict of interest with any financial organization regarding the material discussed in the manuscript.
