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Article History

Received: 17 June 2025

Accepted: 22 December 2025

First Online: 19 January 2026

Declarations

:

: The study, which involves the use of rats as experimental subjects, has undergone rigorous ethical review and has been granted approval by Ethics Committee of Shanghai Chengxi Biotechnology Co., Ltd (Approval Number: CX050804068, Appl.date: 10 August 2024, Number: Eighteen female rats.). The committee has thoroughly evaluated the study protocol to ensure compliance with ethical guidelines for the care and use of laboratory animals. The researchers were fully committed to ensuring the welfare and humane treatment of the animals involved, and all procedures were conducted in strict accordance with the approved protocol. And recognize the ethical obligation to minimize any potential suffering or distress to the animals and will adhere to the principles of the 3Rs throughout the course of the study.”

: Following a thorough review and collaborative discussion among all authors, unanimous consent for the publication of this article has been achieved. Each author has affirmed their commitment to the accuracy and integrity of the research, as well as their willingness to see the work published in the academic community.

: The authors declare no competing interests.