Wang, Zirong
Chai, Yongjia
Pi, Sida
Tuerxun, Dilihumaer
Zhu, Yixuan
Liu, Zihan
Zhang, Huayang
Li, Jingyu
Wang, Chen
Li, Zihao
Kang, Ying
Li, Yanan
Zhao, Na
Tian, Yan
Xiong, Kai
Zhang, Peng
Article History
Received: 25 January 2026
Accepted: 8 June 2026
First Online: 15 June 2026
Declarations
Ethics approval and consent to participate: Publicly available, de-identified GEO datasets were used for the transcriptomic discovery phase and therefore did not require additional institutional ethics approval. The clinical validation component of this study was approved by the Medical Ethics Committee of Tianjin Medical University General Hospital (IRB2025-KY-686). The study was conducted in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines. Written informed consent to participate was obtained from all participants prior to enrollment and blood collection.
Consent for publication: Written informed consent for the procedure and management was obtained from all individual participants included in the study.
Competing interests: The authors declare no competing interests.