Document is current
Any future updates will be listed below
-
Authors
Wang, Liyi
Dai, Xuejun
Ai, Jiao
Li, Xiaojuan
Deng, Aihua
Yang, Xiaomei
Zhang, Ying
Tian, Dujuan
He, Lang
-
Funding
Funding for this research was provided by:
The 2023 Medical Research Project of Chengdu Municipal Health Commission (Project Number: 2023457, 2023349)
The 2023 Teaching Reform Fund Project of Chengdu University of Traditional Chinese Medicine (Project Number: JGJD202305)
The 2022 Nestlé Health Science Oncology Nutrition Research Fund (Project Number: Y-NESTLE2022ON-0486)
- License Information
-
More Information
Article History
Received: 16 February 2025
Accepted: 3 June 2025
First Online: 2 July 2025
Declarations
:
: This study complies with the Declaration of Helsinki. All patients and their families signed informed consent forms, adhering to the principle of voluntary anonymity and fairness, and the study was approved by the Ethics Committee of Chengdu Fifth People’s Hospital (Ethics No: 2023-033(K)-01), and all participants provided written informed consent. This study is not a clinical trial study.
: Written informed consent for publication of the study findings was obtained from all participants or their legal guardians.
: The authors declare no competing interests.
: What is already knownSarcopenia is a common condition among elderly cancer patients and is associated with declines in physical function and quality of life.Nutritional status plays a critical role in the management of sarcopenia and the maintenance of physical function in this population.Although the relationships among sarcopenia, nutritional status, physical function, and quality of life have been investigated, the underlying mechanisms remain inadequately understood.
: This study presents a comprehensive path analysis that elucidates the direct and indirect relationships among sarcopenia, nutritional status, physical function, and quality of life in elderly cancer patients. The results underscore the mediating role of physical function in the link between sarcopenia and quality of life. These findings provide valuable insights into the importance of early detection and targeted interventions for sarcopenia—particularly those aimed at improving nutrition and physical function—to enhance quality of life in this population.
