Werner, Christian https://orcid.org/0000-0003-0679-3227
Fleiner, Tim https://orcid.org/0000-0003-2949-940X
Nerz, Corinna https://orcid.org/0000-0001-5160-796X
Büchele, Gisela https://orcid.org/0000-0001-9881-7796
Haug, Vanessa https://orcid.org/0009-0001-6475-2039
Grüneberg, Christian https://orcid.org/0000-0001-8870-8457
Schäufele, Martina https://orcid.org/0000-0002-9109-7375
Rapp, Kilian https://orcid.org/0000-0003-1625-2571
Bauer, Jürgen M. https://orcid.org/0000-0001-7379-0646
Funding for this research was provided by:
Medizinische Fakultät Heidelberg der Universität Heidelberg
Article History
Received: 3 February 2026
Accepted: 16 March 2026
First Online: 23 March 2026
Declarations
:
: The PromeTheus study was approved by the local ethics committees at each study site (Stuttgart, 732/2020B01; Heidelberg, S-072/2021; Ulm, 26/21) and the Ethics Committee of the State Medical Association Baden-Württemberg (B-F-2021-042), and conducted in accordance with the Declaration of Helsinki. All participants provided written informed consent prior to study inclusion, including consent for the pseudonymized collection, storage, and analysis of study data for research purposes, as described in the participant information and consent form.
: Not applicable.
: The authors declare no competing interests.