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Article History

Received: 23 May 2019

Accepted: 5 August 2019

First Online: 15 August 2019

Ethics approval and consent to participate

: This study was approved by the Institutional Review Board in four research centers - the First Affiliated Hospital of China Medical University, Beijing Youan Hospital Capital Medical University ([2018]-037), the Third People’s Hospital of Shenzhen (2018–007) and Chongqing public health medical center (2018–004-02-KY), and research procedures were carried out strictly in accordance with relevant guidelines ([2018]2015–139-5). Written informed consent will be obtained from each participant prior to starting any study procedure. All research procedures will be carried out strictly in accordance with the Declaration of Helsinki, International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use Guidelines for Good Clinical Practice, and Guidelines for Ethical Review Work of Drug Clinical Trials in China. To ensure privacy, every participant will be uniquely assigned an identification code, in place of his real name, during the survey to link their questionnaire and laboratory testing results.

: Not applicable.

: The authors declare that they have no competing interests.