de Marguerite Nombot-Yazenguet, Marina Prisca
Doté, Joël Wilfried
Koyaweda, Giscard Wilfried
Zemingui-Bembete, Philippe Armand
Selekon, Benjamin
Vickos, Ulrich
Manirakiza, Alexandre
Nakoune, Emmanuel
Gouandjika-Vasilache, Ionela
Komas, Narcisse Patrice Joseph
Funding for this research was provided by:
World Health Organization (2021/1098759-0, 2021/1098759-0)
Article History
Received: 3 November 2023
Accepted: 8 February 2024
First Online: 19 February 2024
Declarations
:
: The research was approved by the Ethics and Scientific Committee of the Faculty of Health Sciences, University of Bangui, Central African Republic (decision number N°38/UB/FACSS/IPB/CES.023) and conducted within the guidelines of the Declaration of Helsinki. Because samples were taken as part of the national surveillance of yellow fever, and that the differential diagnosis of yellow fever is hepatitis E virus infection, the informed consent of the participants was not required.Written informed consent was waived by the « Comité Éthique et Scientifique/Faculté des Sciences, Université de Bangui/Institut Pasteur de Bangui (CES). Hence the CES gave authorization to publish the results from yellow fever national surveillance data used in the differential diagnosis of HEV infection without requiring informed consent. As the state of hepatitis E outbreak had been declared by the Ministry of Health and Population of the Central African Republic in this health district during this time, any person presenting conjunctival jaundice accompanied by a fever had to be systematically sampled for a HEV serological test, and symptomatic treatment was initiated if the serology (anti-HEV-IgM antibodies) of the HEV infection was positive.
: Not applicable.
: The authors declare no competing interests.