Migamba, Stella M.
Ardiet, Denis-Luc
Migisha, Richard
Nansikombi, Hildah T.
Agaba, Brian
Naiga, Helen Nelly
Wanyana, Mercy
Zalwango, Jane Frances
Atuhaire, Immaculate
Kawungezi, Peter Chris
Zalwango, Marie Goretti
Simbwa, Brenda
Kadobera, Daniel
Ario, Alex R.
Harris, Julie R.
Funding for this research was provided by:
U.S. President’s Emergency Plan for AIDS Relief (GH001353–01)
Article History
Received: 23 February 2024
Accepted: 27 May 2024
First Online: 30 May 2024
Declarations
:
: This outbreak investigation was in response to a public health emergency. The Ministry of Health gave a directive to investigate this outbreak and the office of the Center for Global Health, US Center for Disease Control and Prevention determined that this activity was non-research and that its primary intent was for public health practice or disease control. This analysis of the dynamics of transmission of SUDV to household members from primary case-patients was done as part of integrated outbreak analytics (IOA). This activity was reviewed by CDC and was conducted consistent with applicable federal law and CDC policy. § §See e.g., 45 C.F.R. part 46, 21 C.F.R. part 56; 42 U.S.C. § 241(d); 5 U.S.C. § 552a; 44 U.S.C. § 3501 et seq.All SUDV testing was done for diagnostic purposes as part of the public health emergency response to the outbreak in Uganda, and thus was not subject to institutional review board clearance. Test results were released by the Uganda Virus Research Institute (UVRI) laboratory to the relevant public health authorities according to protocol. We included households and individuals who consented to the interviews. The authors sought permission to conduct the study from district health authorities and local government leaders of Mubende and Kassanda districts.Verbal informed consent was sought from study participants who were at least 18 years old or their parents/guardians for those below 18 years. The authors also sought assent from participants below the age of 18 years. For those who had died, informed consent was obtained from their next-of-kin. The interviewers took the participants/guardians through the informed consent section and obtained consent before proceeding with interviews. The choice of verbal over written consent was made so as to minimise the possible risk of Ebola transmission. Each study participant was assigned a unique identifier to protect their confidentiality. All methods were conducted consistent with relevant guidelines and regulations.
: Not applicable.
: The authors declare no competing interests.