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Authors
Lihou, Katie
Challen, Robert
Chatzilena, Anastasia
Qian, George
Oben, Glenda
King, Jade
McGuinness, Serena
Morales-Aza, Begonia
Duale, Kaltun
Pereira, Ainhoa Rodriguez
Healy, William
Oliver, Jennifer
Maskell, Nick
Finn, Adam
Danon, Leon
Hyams, Catherine
,
Sinclair, Aaran
Langdon, Amelia
Taylor, Amy
Turner, Anabella
Jones, Anna
Koi, Anna
Mattocks, Anya
Osborne, Bethany
Dooley, Brianna
Hawkins, Callum
Grimes, Charli
Farren, Chloe
Povey, Christian
Mitchell, Claire
Adegbite, David
Thomas, Dylan
Balch, Elinor
Ackroyd-Weldon, Ella
Bridgeman, Emma
Scott, Emma
Wright, Felix
Davies, Ffion
Perkins, Fiona
Bayley, Francesca
Ruffino, Gabriella
Valentine, Gabriella
Mortimer, Georgina
Tilzey, Grace
Ibbotson, Harriet
Batholomew, Hanah
Swift, Hugo
Symanowski, Jacob
Kelland, Ilana
Ely, Imogen
Whittle, Jake
Kinney, Jane
Wright, Johanna Kellett
Vowles, Jonathan
Bonnici, Josephine
Anderson, Josh
Garcia-Tello, Juan
Brzezinska, Julia
Cloake, Julie
Milutinovic, Katarina
Helliker, Kate
Maughan, Katie
Fox, Kazminder
Pettinger, Kellie
Minou, Konstantina
Chandler, Kyla
Ward, Lana
Fleming, Leah
Morrison, Leigh
Smith, Liberty
Smart, Lily
Grimmer, Lisa
Setter, Louise
Wright, Louise
Grimwood, Lucy
Bellavia, Maddalena
Clout, Madeleine
Lyall, Maia
Eghleilib, Malak
Vasquez, Marianne
Gonzalez, Maria Garcia
Ardeshir, Mariella
Mergulhao, Marta
Chmelarova, Martina
Randell, Matthew
Booth, Michael
Jeenes-Flanagan, Milo
Resutikova, Miriama
Chaulagain, Monika
Chang, Natalie
Tavira, Nefeli
Farhoudi, Nellie
Grace, Niall
Manning, Nicola
Griffiths, Oliver
Pearce, Olivia
Croxford, Pip
Sequenza, Peter
Anchidin, Petronela
Lazarus, Rajeka
Clemence, Rebecca
Aldridge, Rosa
Walters, Rhian
Cooper, Riley
Marlow, Robin
Heath, Robyn
Antico, Rupert
Arachchge, Sandi Nammuni
Stollery, Sarah
Suppiah, Seevakumar
Robinson, Sean
Uddin, Siddiqa
Mona, Taslima
Riaz, Tawassal
Barrett, Teagan
Long, Tom
Dimofte, Tudor
Khoud, Yassin Ben
Mackay, Vicki
Hashmi, Zahra
Maseko, Zandile
Taylor, Zoe
Szasz-Benczur, Zsuzsa
Friedrich, Zsolt
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Funding
Funding for this research was provided by:
Pfizer UK
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Article History
Received: 27 February 2025
Accepted: 24 June 2025
First Online: 21 August 2025
Declarations
:
: This prospective observational cohort study of adults admitted to two large university hospitals (Southmead, and Bristol Royal Infirmary) in Bristol, UK, was conducted in accordance with the International Conference for Harmonisation of Good Clinical Practice (ICCH GCP), the UK Policy Framework for Health and Social Care Research, and the Declaration of Helsinki, and was approved by the East of England—Essex Research Ethics Committee, Health Research Authority reference 20/EE/0157, ISRCTN: 17354061. Informed consent was obtained from patients with capacity, and declarations for participation from consultees for individuals lacking capacity. If it was not practicable to approach individuals for consent, data were included using approval from the Clinical Advisory Group under Sect. 251 of the 2006 NHS Act. Clinical trial number: not applicable.
: CH is Principal Investigator of the AvonCAP study which is an investigator-led University of Bristol study funded by Pfizer and has previously received support from the NIHR in an Academic Clinical Fellowship. JO is a Co-Investigator on the AvonCAP Study. LD is further supported by UKRI through the JUNIPER consortium (grant number MR/V038613/1), MRC (grant number MC/PC/19067), EPSRC (EP/V051555/1 and The Alan Turing Institute, grant EP/N510129/1). AF was a member of the Joint Committee on Vaccination and Immunization (JCVI) until January 2024 and remains a member of the JCVI RSV subcommittee. In addition to receiving funding from Pfizer as Chief Investigator of this study, he leads another project investigating transmission of respiratory bacteria in families jointly funded by Pfizer and the Gates Foundation and is an investigator in trials of COVID-19 vaccines including ChAdOx1nCOV-19, Janssen, Sanofi and Valneva vaccines. NM is supported by the National Institute for Health and Care Research Bristol Biomedical Research Centre. The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care. This study was conducted as a collaboration between The University of Bristol (study sponsor) and Pfizer (study funder).
