de Oliveira, Viviane Lago https://orcid.org/0000-0002-9024-3107
Almeida, Taynná Vernalha Rocha
da Silva Junior, Heiner Borges
Abrahim Alves, Taysa Litaiff Isper
Boechat, Antônio Luiz
Chaves, Yury Oliveira
João, Guilherme Augusto Pivoto
de Almeida e Val, Fernando Fonseca
dos Reis, Monique Freire
de Lima Ferreira, Luiz Carlos
Gonçalves, Roberta Lins
Funding for this research was provided by:
Fundação de Amparo à Pesquisa do Estado do Amazonas
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (88887.200582/2018-00, 88887.200582/2018-00, 88887.200582/2018-00, 88887.200582/2018-00)
Article History
Received: 26 July 2025
Accepted: 16 October 2025
First Online: 12 November 2025
Declarations
:
: This study was conducted in accordance with the Declaration of Helsinki and was approved by the Ethics and Research Committee of the Fundação de Medicina Tropical Doutor Heitor Vieira Dourado (CEP/FMT-HVD), under the following protocol numbers: CAAE: 98665118.6.0000.0005, Opinion No. 2.227.259, and retrospective approval No. 4.882.245. Given the retrospective nature of the study and the exclusive use of anonymized data extracted from medical records, obtaining individual informed consent from participants was not feasible. In accordance with Brazilian regulations — Resolutions No. 466/2012 and No. 510/2016 of the National Health Council — a formal waiver of informed consent was granted by the CEP/FMT-HVD. The research team also signed a Term of Commitment for Data Use (TCUD), ensuring confidentiality and ethical handling of all data collected. This waiver is formally documented and available upon request.
: Not applicable.
: The authors declare no competing interests.