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Authors
Zhou, Yihong
Qin, Yuanyuan
Liu, Xia
Zhao, Qingxia
Wang, Min
Chen, Yuanyuan
Li, Ying
He, Kun
Li, Xiaofeng
Harypursat, Vijay
Xie, Dong
Chen, Yaokai
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Funding
Funding for this research was provided by:
the Chongqing medical scientific research project (2026KFXM067)
the Chongqing medical scientific research project (2024QNXM050)
the Chongqing medical scientific research project (2024MSXM117)
the Chongqing medical scientific research project (2024MSXM153)
the Chongqing medical scientific research project (2026DBXM001)
Medical Youth Top-Talent Project in Chongqing (YXQN202580)
the Prevention and Control of Emerging and Major Infectious Diseases-National Science and Technology Major Project (2025ZD01904904)
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Article History
Received: 11 December 2025
Accepted: 25 February 2026
First Online: 28 March 2026
Declarations
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: This study was approved by the institutional review boards of all participating centers in China: Chongqing Public Health Medical Center (2020-078-01), The Sixth People’s Hospital of Zhengzhou (IEC-2021-016-01), and First Hospital of Changsha (20210203CSSY00102). The study was also approved by the Advarra Institutional Review Board, USA (IRB #: Pro00044499). All procedures involving human participants were conducted in accordance with the ethical standards of the relevant institutional and/or national research committees and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. Written informed consent was obtained from all participants prior to enrollment.
: Not applicable.
: In accordance with the journal’s policy on competing interests, the authors disclose the following: DX is an employee of Frontier Biotechnologies Inc. and receives research funding from the company. XL receives salary support from Frontier Biotechnologies Inc. All authors have unrestricted access to the study data and analyses and have approved the final version of the manuscript. All other authors have declared that no competing interests exist. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest.
