Funding for this research was provided by:
National Natural Science Foundation of China (82271993)
Article History
Received: 17 February 2026
Accepted: 22 April 2026
First Online: 25 April 2026
Declarations
:
: This study complied to the Declaration of Helsinki, approved by the Ethics Committee of Shandong Provincial Hospital (SWYX: NO.2020 − 170), and all participants provided written informed consent.
: Not applicable.
: This trial was prospectively registered with the Chinese Clinical Trial Registry on May 09, 2022 (registration number: ChiCTR2200059723).
: The authors declare no competing interests.